NF-κB Activation Inhibitor III
Catalogue number:
CAY19083-5 mg
Supplier:
Size:
5 mg
Product is available in:
£113.00
Estimated delivery Mon 17 Nov
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
380623-76-7
Purity:
≥99%
Formulation:
A solid
Molecular Formula:
C10H5ClN4O5S
Molecular Weight:
328.7
Alternative Names:
3-chloro-4-nitro-n-(5-nitro-2-thiazolyl)-benzamide, sm-7368
Product Description:
An inhibitor of NF-κB activation; inhibits TNF-α-induced NF-κB activation in HT-1080 cells at 20 µM; inhibits TNF-α-induced expression of MMP-9 in HT-1080 cells; decreases TNF-α-induced migration of HT-1080 cells at 20 µM; inhibits IL-6 release induced by TNF-α from primary rat brain pericytes at 1, 5, and 10 µM; increases IL-8 secretion in HT-29 and Caco-2 cells at 5 µM in combination with glyoxal
