JNJ-7706621
Catalogue number:
CAY18494-1 mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
443797-96-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C15H12F2N6O3S
Molecular Weight:
394.4
Alternative Names:
4-[[5-amino-
Product Description:
A dual inhibitor of Cdks and Aurora kinases; inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk3/cyclin E, Cdk4/cyclin D1, Cdk6/cyclin D1, Aurora A, and Aurora B in vitro (IC50s = 9, 4, 3, 58, 253, 175, 11, and 15 nM, respectively); blocks the growth of cancer cells in vitro and in vivo
