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JNJ-7706621

Catalogue number:
CAY18494-1 mg
Supplier:
Size:
1 mg
Product is available in:
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£62.00 Estimated delivery Wed 14 Jan
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

443797-96-4

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C15H12F2N6O3S

Molecular Weight:

394.4

Alternative Names:

4-[[5-amino-1-(2,6-difluorobenzoyl)-1h-1,2,4-triazol-3-yl]amino]-benzenesulfonamide, aurora a inhibitor i, aurora kinase/cdk inhibitor

Product Description:

A dual inhibitor of Cdks and Aurora kinases; inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk3/cyclin E, Cdk4/cyclin D1, Cdk6/cyclin D1, Aurora A, and Aurora B in vitro (IC50s = 9, 4, 3, 58, 253, 175, 11, and 15 nM, respectively); blocks the growth of cancer cells in vitro and in vivo

CAY18494-1 mg: JNJ-7706621
CAY18494-1 mg: JNJ-7706621