OSI-027
Catalogue number:
CAY17379-5 mg
Supplier:
Size:
5 mg
Product is available in:
£170.00
Estimated delivery Wed 24 Sep
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
936890-98-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H22N6O3
Molecular Weight:
406.4
Alternative Names:
trans-4-[4-amino-5-(7-methoxy-1h-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-cyclohexanecarboxylic acid
Product Description:
An inhibitor of the catalytic site of mTOR, inhibiting both mTORC1 and mTORC2 (IC50s = 22 and 65 nM, respectively); prohibits proliferation, induces autophagy, and potentiates apoptosis in BCR-ABL transformed cells and other cancer cells at 10 µM; effective in vivo
