Bindarit
Catalogue number:
CAY11479-25 mg
Supplier:
Size:
25 mg
Product is available in:
£348.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
130641-38-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H20N2O3
Molecular Weight:
324.4
Alternative Names:
2-
- MSDS: View or download
Product Description:
An inhibitor of MCP production; selective for MCP-1/CCL2, MPC-3/CCL7, and MCP-2/CCL8; inhibits LPS- or C. albicans-induced production of MCP-1/CCL2 in isolated human monocytes (IC50s = 172 and 403 µM, respectively); delays the onset of proteinuria and prolongs survival in a mouse model of experimental lupus nephritis at 50 mg/kg; prevents LPS-induced increases in MCP-1/CCL2 expression in mouse brain and spinal cord when administered at a dose of 200 mg/kg; a noncompetitive inhibitor of MCT4 (Ki = 30.2 µM) that is selective for MCT4 over MCT1
