INT-777
Catalogue number:
CAY17678-500 ug
Supplier:
Size:
500 µg
Product is available in:
£170.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1199796-29-6
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C27H46O5
Molecular Weight:
450.7
Alternative Names:
(3α,5β,6α,7α,12α,23s)-
Product Description:
An agonist of TGR5 (EC50 = 0.82 µM); stimulates the secretion of GLP-1 in mice when given orally (30 mg/kg) after a glucose challenge, particularly when given with a DPP4 inhibitor; increases energy expenditure and reduces hepatic steatosis and adiposity in mice subjected to diet-induced obesity
