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GSK484 (hydrochloride)

Catalogue number:
CAY17488-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
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£291.00 Estimated delivery Fri 10 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1652591-81-5

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C27H31N5O3 • HCl

Molecular Weight:

510

Alternative Names:

[(3s,4r)-3-amino-4-hydroxy-1-piperidinyl][2-[1-(cyclopropylmethyl)-1h-indol-2-yl]-7-methoxy-1-methyl-1h-benzimidazol-5-yl]-methanone, monohydrochloride

Product Description:

A reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme; blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of NETs in both mouse and human neutrophils

CAY17488-5 mg: GSK484 (hydrochloride)
CAY17488-5 mg: GSK484 (hydrochloride)