Erastin
Catalogue number:
CAY17754-5 mg
Supplier:
Size:
5 mg
Product is available in:
£222.00
Estimated delivery Mon 15 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
571203-78-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C30H31ClN4O4
Molecular Weight:
547.1
Alternative Names:
2-
Product Description:
A ferroptosis inducer; induces ferroptotic cell death in vitro, an effect that can be blocked by ferroptosis inhibitors; inhibits cystine uptake by the system xc- cystine-glutamate transporter in HT-1080 fibrosarcoma and Calu-1 lung carcinoma cells at 5 µM; inhibits glutamate release via the cystine-glutamate transporter in an enzyme-coupled fluorescence assay (EC50 = 1.2 µM); selectively induces cell death in cells expressing the SV40 small T oncoprotein and oncogenic Ras (IC50s = 1.25-5 µg/ml)
