Erastin
Catalogue number:
CAY17754-1 mg
Supplier:
Size:
1 mg
Product is available in:
£69.00
Estimated delivery Mon 4 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
571203-78-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C30H31ClN4O4
Molecular Weight:
547.1
Alternative Names:
2-
Product Description:
A ferroptosis inducer; induces ferroptotic cell death in vitro, an effect that can be blocked by ferroptosis inhibitors; inhibits cystine uptake by the system xc- cystine-glutamate transporter in HT-1080 fibrosarcoma and Calu-1 lung carcinoma cells at 5 µM; inhibits glutamate release via the cystine-glutamate transporter in an enzyme-coupled fluorescence assay (EC50 = 1.2 µM); selectively induces cell death in cells expressing the SV40 small T oncoprotein and oncogenic Ras (IC50s = 1.25-5 µg/ml)
