GKT137831
Catalogue number:
CAY17764-10 mg
Supplier:
Size:
10 mg
Product is available in:
£174.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1218942-37-0
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C21H19ClN4O2
Molecular Weight:
394.9
Alternative Names:
2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1h-pyrazolo[4,3-c]pyridine-3,6(2h,5h)-dione
Product Description:
A dual inhibitor of both NOX1 and NOX4 with Ki values in the range of 100 to 150 nM in cell-free assays of ROS production; displays good oral bioavailability with high plasma concentrations in vivo and attenuates liver fibrosis in mice




