BIIB-057
Catalogue number:
CAY17652-5 mg
Supplier:
Size:
5 mg
Product is available in:
£262.00
Estimated delivery Mon 29 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1370261-96-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H23N9O
Molecular Weight:
393.5
Alternative Names:
2-[[(1r,2s)-2-aminocyclohexyl]amino]-4-[[3-(2h-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide, p505-15, prt062607, prt2607
Product Description:
A potent, selective, orally bioavailable inhibitor of Syk (IC50 = 1 nM); blocks B cell receptor-mediated cell signaling and activation in whole blood (IC50s = 0.27 and 0.28 µM, respectively); inhibits inflammation and tumor growth in animal models of rheumatoid arthritis and non-Hodgkin lymphoma, respectively
