CAY10682
Catalogue number:
CAY15574-1 mg
Supplier:
Size:
1 mg
Product is available in:
£148.00
Estimated delivery Thu 23 Oct
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1542066-74-9
Alternative Names:
4-(4-bromophenyl)-1-[(4-fluorophenyl)methyl]-4,5-dihydro-5-[3-(1h-imidazol-1-yl)propyl]-3-phenyl-pyrrolo[3,4-c]pyrazol-6(1h)-one
Product Description:
Inhibits the p53-Mdm2 interaction (Ki = 83 nM) and also dose-dependently reduces activation of the NF-κB pathway; prevents phosphorylation of IκBα by IKKα, IKKβ, and IKKɛ (IC50s = 80.5, 78.2, and 57.1 µM, respectively); inhibits the growth of A549 cell xenografts in mice
