Carmofur
Catalogue number:
CAY14243-500 mg
Supplier:
Size:
500 mg
Product is available in:
£84.00
Estimated delivery Thu 18 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
61422-45-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C11H16FN3O3
Molecular Weight:
257.3
Alternative Names:
5-fluoro-n-hexyl-3,4-dihydro-2h,4-dioxo-1-pyrimidinecarboxamide, hcfu
- MSDS: View or download
Product Description:
A selective inhibitor of acid ceramidase (IC50 = 79 nM for rat acid ceramidase); reduces acid ceramidase activity and induces intracellular accumulation of various ceramide species in SW403 colon and LNCaP prostate cancer cells; induces apoptosis in SW403 cells without inhibiting DNA synthesis (IC50 = 1,212 mM for human thymidylate synthetase); reduces acid ceramidase activity and increases ceramide accumulation in mouse lung and brain at 10 and 30 mg/kg
