DABCYL acid is the abbreviation of 4-(dimethylaminoazo)benzene-4-carboxylic acid. In some literature, DABSYL (4-dimethylaminoazobenzene-4'-sulfonyl chloride) is misused as ‘DABCYL’. DABCYL is one of the most popular acceptors for developing FRET-based nucleic acid probes and protease substrates. DABCYL dyes are often paired with EDANS in FRET-based fluorescent probes.
Reagents & Kit Components
-20°C desiccated and protected from light
Minimum Purity: 98%
1. Kuhn H, et al. (2001). Antisense Nucleic Acid Drug Dev 11, 265-70.2. Lam TL, et al. (2000). Life Sci 67, 2889-96.3. Maggiora LL, et al. (1992). J Med Chem 35, 3727-30.