This is a cyclic derivative of RGD having a high affinity for αvβ3 integrin. It is considered the most prominent structure for the development of molecular imaging compounds in order to determine αvβ3 expression. It has been shown that both purified and membrane-bound αvβ3 intergrin binds to c(RGDyK) with high affinity.
Proteins & Peptides
Peak Area by HPLC ≥95%
1, Huang, X-W. et al. Biochemical Pharmacology 80, 136–143 (2010). 2, Chen, X. et al. Bioconjug. Chem. 15, 41 (2004).