IKKγ NEMO Binding Domain (NBD) Inhibitory Peptide - ANA61169 - 1 mg - AnaSpec - proteins & peptides

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.