IKKγ NEMO Binding Domain (NBD) Inhibitory Peptide
Supplier:
Catalogue number:
ANA61169
Size:
1 mg
Product is available in:
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.
Product Type:
Proteins & Peptides
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
3693.3
Reference:
Ref: Paria, B. et al. J. Biol. Chem. 278, 37195 (2003); Tian, M. et al. Blood May 2005(10.1182/blood-2004-04-1248); Bharti, A. Blood 101, 1053 (2003).
UNSPSC Code:
12352202
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