HCV NS3/4A protease, recombinant 5 µg
Catalogue number:
ANA61017-5
Supplier:
Size:
5 µg _$$_
Product is available in:
£432.00
Estimated delivery Thu 25 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
Purity:
≥95% by SDS-PAGE
Molecular Weight:
22.7
Product Description:
NS3 protease of hepatitis C virus (HCV), located on the N-terminal domain of HCV NS3, is responsible for the cleavage at the NS3/NS4A, NS4A/NS4B, NS4B/NS5A, and NS5A/NS5B sites of the nonstructural protein. The HCV NS3 is a chymotrypsin-like serine protease. It requires a cofactor, a 54 amino acid NS4 protein, to reach its optimal activity. The X-ray crystal structure studies show that NS3 forms a tight non-covalent complex with NS4. The NS3/4A protease is essential for viral replication and the formation of infectious viral particles, and thus has been considered as one of the most attractive targets for anti-HCV therapy.
Storage Temperature:
-78°C