β-Amyloid (1-42), HL488-labeled

Aβ (1-42), a major component of amyloid plaques, accumulates in neurons of Alzheimer’s disease brains. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Aβ (1-42) is the principal species associated with senile plaque amyloids, while Aβ (1-40) is more abundant in cerebrovascular amyloid deposit. This is a fluorescent (HiLyte™ Fluor 488)-labeled β-Amyloid peptide, Abs/Em=503/528 nm. Hilyte™ Fluor 488 labeled Aβ (1-42) has a brighter intensity than FAM-labeled Aβ (1-42).