LY2940680
Catalogue number:
CAY16264-1 mg
Supplier:
Size:
1 mg
Product is available in:
£78.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1258861-20-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C26H24F4N6O
Molecular Weight:
512.5
Alternative Names:
4-fluoro-n-
Product Description:
A Smo antagonist; inhibits [35S]GTPγS binding in CHO cells expressing wild-type Smo (IC50 = 294 nM); reduces production of GLI1 mRNA induced by sonic hedgehog (Shh) in Daoy cells (IC50 = 5.49 nM); topical application decreases skin GLI1 and PTCH1 mRNA expression in depilated mice at 2% w/v
