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GNE-7915

Catalogue number:
CAY16252-50 mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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£762.00 Estimated delivery Wed 21 Jan
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1351761-44-8

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C19H21F4N5O3

Molecular Weight:

443.4

Alternative Names:

[4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-methanone

Product Description:

A selective, brain-penetrable LRRK2 inhibitor (Kis = 2 and 18.7 nM in biochemical and cell-based assays, respectively); inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson’s disease mutation (IC50 = 20 nM in vivo)

CAY16252-50 mg: GNE-7915
CAY16252-50 mg: GNE-7915