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Cariporide

Catalogue number:
CAY16935-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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£152.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

159138-80-4

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C12H17N3O3S

Molecular Weight:

283.3

Alternative Names:

n-(aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide, hoe 642

Product Description:

An NHE-1 inhibitor (IC50 = 0.56 µM in an intracellular pH recovery assay); selective for NHE-1 over NHE-2 (IC50 = 28 µM in an intracellular pH recovery assay); inhibits sodium propionate-induced swelling of isolated human platelets (IC50 = 0.023 µM); reduces the myocardial infarct size as a percentage of the area at risk in a rabbit model of ischemia-reperfusion injury induced by coronary artery occlusion at 1 mg/kg; decreases ventricular tachycardia duration in a rat model of coronary artery ligation and reperfusion-induced arrhythmia at 1 mg/kg

CAY16935-10 mg: Cariporide
CAY16935-10 mg: Cariporide