Wnt-C59
Catalogue number:
CAY16644-1 mg
Supplier:
Size:
1 mg
Product is available in:
£56.00
Estimated delivery Wed 24 Sep
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1243243-89-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C25H21N3O
Molecular Weight:
379.5
Alternative Names:
4-(2-methyl-4-pyridinyl)-n-[4-(3-pyridinyl)phenyl]-benzeneacetamide, porcn inhibitor ii
Product Description:
A potent inhibitor of PORCN (IC50 = 74 pM), completely blocking Wnt secretion into culture media; prevents activation of all evaluated Wnt family members; effective in vivo as well as in vitro; blocks the progression of breast cancer while downregulating Wnt/β-catenin pathway target genes in mice