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Halofuginone (hydrochloride)

Catalogue number:
CAY13370-1 mg
Supplier:
Size:
1 mg
Product is available in:
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£276.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1217623-74-9

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C16H17BrClN3O3 • HCl

Molecular Weight:

451.1

Alternative Names:

7-bromo-6-chloro-3-[3-[(2r,3s)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3h)-quinazolinone, monohydrochloride

Product Description:

A halogenated derivative of febrifugine that down-regulates Smad3, blocking TGF-β signaling relevant to fibrosis and tumor progression in a variety of different models; competitively inhibits prolyl-tRNA synthetase (Ki = 18.3 nM), preventing the differentiation of TH17 cells and blunting an autoimmune response

CAY13370-1 mg: Halofuginone (hydrochlori
CAY13370-1 mg: Halofuginone (hydrochloride)