Isofagomine (D-tartrate)
Catalogue number:
CAY16137-1 mg
Supplier:
Size:
1 mg
Product is available in:
£103.00
Estimated delivery Wed 1 Oct
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
957230-65-8
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C6H13NO3 • C4H6O6
Molecular Weight:
297.3
Alternative Names:
5r-(hydroxymethyl)-3r,4r-piperidinediol, mono 2s,3s-dihydroxybutanedioate
Product Description:
A competitive inhibitor of human lysosomal β-glucosidase (Ki = 0.016-0.025 µM; IC50 = 0.06 µM) that interacts with the catalytic pocket of β-glucosidase, acting as a chemical chaperone that stabilizes and/or promotes the folding of the enzyme; increases lysosomal β-glucosidase activity by 2- to 3-fold in mutant N370S Gaucher fibroblasts
