JNK Inhibitor VIII
Catalogue number:
CAY15946-10 mg
Supplier:
Size:
10 mg
Product is available in:
£243.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
894804-07-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H20N4O4
Molecular Weight:
356.4
Alternative Names:
n-
Product Description:
An inhibitor of JNK1, JNK2, and JNK3 (Kis= 2, 4, and 52 nM, respectively); selective for JNK1, JNK2, and JNK3 over a panel of 74 kinases (Kis = >720 nM for all); inhibits the phosphorylation of c-Jun in HepG2 cells (EC50 = 920 nM); inhibits NGF-induced neuronal growth and proNGF-induced neurotoxicity of primary mouse superior cervical ganglion neurons at 10 µM; reduces apoptosis induced by GPX1 siRNA knockdown in HeLa cells at 10 µM
