Ganglioside GT1b (bovine) (sodium salt)
Catalogue number:
CAY15588-5 mg
Supplier:
Size:
5 mg
Product is available in:
£584.00
Estimated delivery Tue 27 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥98%
Formulation:
A lyophilized solid
Molecular Formula:
C95H162N5O47 • 3Na (for stearoyl)
Molecular Weight:
2126.3
Alternative Names:
ganglioside g1, trisialoganglioside gt1b
Product Description:
A mixture of ganglioside GT1b with C18:1 and C20:1 sphingoid backbones; characterized by having two sialic residues linked to the inner galactose unit; binds to the neurotoxins BTxA, BTxA heavy chain, and tetanus toxin (IC50s = 11, 0.74, and 7.2 µM, respectively); ganglioside GT1b-containing liposomes can bind to the major coat protein VP1 from MCPyV; a putative MCPyV receptor; decreases production of IL-6, IL-10, IgG, IgM, and IgA in human PBMCs by 31.4, 30.5, 60, 59.5, and 58%, respectively, at 10 µM
