Ganglioside GT1b (bovine) (sodium salt)
Catalogue number:
CAY15588-5 mg
Supplier:
Size:
5 mg
Product is available in:
£501.00
Estimated delivery Tue 2 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥98%
Formulation:
A lyophilized solid
Molecular Formula:
C95H162N5O47 • 3Na (for stearoyl)
Molecular Weight:
2126.3
Alternative Names:
ganglioside g1, trisialoganglioside gt1b
Product Description:
A mixture of ganglioside GT1b with C18:1 and C20:1 sphingoid backbones; characterized by having two sialic residues linked to the inner galactose unit; binds to the neurotoxins BTxA, BTxA heavy chain, and tetanus toxin (IC50s = 11, 0.74, and 7.2 µM, respectively); ganglioside GT1b-containing liposomes can bind to the major coat protein VP1 from MCPyV; a putative MCPyV receptor; decreases production of IL-6, IL-10, IgG, IgM, and IgA in human PBMCs by 31.4, 30.5, 60, 59.5, and 58%, respectively, at 10 µM
