KMN-80
Catalogue number:
CAY15435-1 mg
Supplier:
Size:
1 mg
Product is available in:
£214.00
Estimated delivery Tue 16 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1628759-75-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H33NO4
Molecular Weight:
363.5
Alternative Names:
7-
Product Description:
A selective, potent agonist of EP4 with an IC50 value of 3 nM (versus 1.4 µM for EP3 and > 10 µM for all other prostanoid receptors) and an EC50 value of 0.19 nM in functional assays; induces the differentiation of bone marrow stem cells from both young and aged rats into osteoblasts in vitro (EC50s = 20 and 153 nM, respectively); repairs calvarial defects in an in vivo rat craniomaxillofacial reconstruction model and promotes bone formation in a rat incisor tooth socket model
