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CAS Number:
141136-83-6
Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
748.9
- Data sheet: View or download
Product Description:
This peptide corresponds to aa 42-47 of protease-activated receptor-1 (PAR-1) generated upon thrombin cleavage. This sequence is a PAR agonist, acting as a tethered peptide ligand. Free SFLLRN activates PAR-1 independent of receptor cleavage and has been used to probe PAR-1 function in various cells and tissues. This peptide is also known to be capable of activating PAR-2.