ML-216
Catalogue number:
CAY15186-10 mg
Supplier:
Size:
10 mg
Product is available in:
£152.00
Estimated delivery Wed 12 Nov
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1430213-30-1
Alternative Names:
n-[4-fluoro-3-(trifluoromethyl)phenyl]-n'-[5-(4-pyridinyl)-1,3,4-thiadiazol-2-yl]-urea, cid-49852229
Product Description:
The first identified small molecule inhibitor of BLM helicase (IC50 = 1.8 µM) that is 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s ≥ 50 µM); 25-50 µM dose-dependently inhibits the proliferation of BLM-expressing PSNF5 fibroblast cells
