CUR 61414
Catalogue number:
CAY14931-5 mg
Supplier:
Size:
5 mg
Product is available in:
£152.00
Estimated delivery Wed 12 Nov
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
334998-36-6
Alternative Names:
n-[(3s,5s)-1-(1,3-benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-n-[(3-methoxyphenyl)methyl]-3,3-dimethyl-butanamide, g-856
Product Description:
A potent inhibitor of hedgehog-induced cellular activity (IC50 = 100-200 nM); binds directly with the pathway activator Smo (Ki = 44 nM); blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of basaloid lesions triggered by ultraviolet light in mouse skin
