Panobinostat
Catalogue number:
CAY13280-5 mg
Supplier:
Size:
5 mg
Product is available in:
£37.00
Estimated delivery Wed 12 Nov
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
404950-80-7
Alternative Names:
(2e)-n-hydroxy-3-[4-[[[2-(2-methyl-1h-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide, lbh-589
Product Description:
A pan-HDAC inhibitor (Kis = 0.6-31 nM for HDAC1-11); inhibits growth in a panel of 37 human or mouse lung cancer cell lines, including SCLC, NSCLC, and mesothelioma cells (IC50s = 4-175, 5-310, and 5-470 nM, respectively); induces tumor regression in BK-T and RG-1 SCLC mouse xenograft models at 20 mg/kg i.p.
