www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

ML-265

Catalogue number:
CAY13942-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£37.00 Estimated delivery Thu 21 May
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1221186-53-3

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C17H16N4O2S2

Molecular Weight:

372.5

Alternative Names:

6-[(3-aminophenyl)methyl]-4,6-dihydro-4-methyl-2-(methylsulfinyl)-5h-thieno[2’,3’:4,5]pyrrolo[2,3-d]pyridazin-5-one, cid-44246499, ncgc00186528, tepp-46

Product Description:

A selective activator of tumor-specific PKM2 (EC50 = 92 nM) that binds to the dimer-dimer interface between two subunits of PKM2, inducing tetramerization; 50 mg/kg reduces tumor size, weight, and occurrence in mice bearing H1299 cell xenografts in a model of human non-small cell lung carcinoma

CAY13942-1 mg: ML-265
CAY13942-1 mg: ML-265