ALK5 Inhibitor II
Catalogue number:
CAY14794-10 mg
Supplier:
Size:
10 mg
Product is available in:
£203.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
446859-33-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C17H13N5
Molecular Weight:
287.3
Alternative Names:
2-
Product Description:
A selective inhibitor of the TGF-β type1 receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-β cellular assay, and ALK5 binding in HepG2 cells, respectively); used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription
