Bosutinib
Catalogue number:
CAY12030-100 mg
Supplier:
Size:
100 mg
Product is available in:
£539.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
380843-75-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C26H29Cl2N5O3
Molecular Weight:
530.5
Alternative Names:
4-
- MSDS: View or download
Product Description:
An inhibitor of c-Src and Abl kinases (IC50s = 1.2 and 1 nM, respectively); inhibits the kinases EPHB2, TrkA, TrkB, and TXK (IC50s = 8.5, 22, 27, and 40 nM, respectively) among others; inhibits Src-dependent cell proliferation (IC50 = 100 nM); reduces tumor growth in unstaged and staged Src-transformed fibroblast mouse xenograft models at 30 or 25 mg/kg, respectively, twice per day; induces complete tumor regression in a K562 mouse xenograft model at 100 mg/kg once per day for five days
