2-deoxy-D-Glucose
Catalogue number:
CAY14325-1 g
Supplier:
Size:
1 g
Product is available in:
£74.00
Estimated delivery Mon 8 Jun
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
154-17-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C6H12O5
Molecular Weight:
164.2
Alternative Names:
2-
- MSDS: View or download
Product Description:
A glucose antimetabolite and an inhibitor of glycolysis; metabolized into 6-DG6P, which cannot be metabolized by glucose-6-phosphate isomerase, leading to 2-DG6P accumulation, inhibition of glycolysis, and cell death; induces apoptosis in SK-BR-3 cells at 16 mM; inhibits the growth of 143B osteosarcoma cells cultured under hypoxic conditions at 2 mg/ml; reduces tumor growth in 143B osteosarcoma and MV522 non-small cell lung cancer mouse xenograft models when used alone or in combination with doxorubicin or paclitaxel at 500 mg/kg
