3-Deazaneplanocin A (hydrochloride)
Catalogue number:
CAY11102-5 mg
Supplier:
Size:
5 mg
Product is available in:
£664.00
Estimated delivery Fri 22 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
120964-45-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C12H14N4O3 • HCl
Molecular Weight:
298.7
Alternative Names:
5r-(4-amino-
- MSDS: View or download
Product Description:
An analog of 3-deazaadenosine, an inhibitor of SAH hydrolase; depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in primary human AML cells in a dose-dependent manner (0.2-1 µM); acts synergistically with the pan-HDAC inhibitor panobinostat in inducing apoptosis of AML cells implanted in mice
