Cl-Amidine (hydrochloride)
Catalogue number:
CAY10599-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£287.00
Estimated delivery Tue 30 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1373232-26-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
347.2
Alternative Names:
n-[(1s)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide, monohydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PAD inhibitor (IC50s = 0.8, 6.2, and 5.9 µM for PAD1, PAD3, and PAD4, respectively); cytotoxic to HL-60, MCF-7, and HT-29 cancer cells (IC50s = 0.25, 0.05, and 1 µM, respectively); reduces ex vivo extracellular NET formation and increases survival in a mouse model of CLP-induced sepsis at 50 mg/kg; decreases the citrulline content in serum and joints and reduces the development of IgG autoantibodies in a mouse model of collagen-induced arthritis
Storage Temperature:
-20°C
