GSK1059615
Catalogue number:
CAY11569-5 mg
Supplier:
Size:
5 mg
Product is available in:
£118.00
Estimated delivery Tue 4 Nov
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
958852-01-2
Alternative Names:
5z-[[4-(4-pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione
Product Description:
A potent, reversible, ATP-competitive, thiazolidinedione inhibitor of PI3Kα (IC50 = 2 nM) and the common activating mutants of p100α (E542K, E545K, and H1047R) found in cancer; prevents proliferation in BT474 tumor xenografts and reduces MAPK signaling with twice daily dosing at 25 mg/kg
