17-AAG
Catalogue number:
CAY11039-1 mg
Supplier:
Size:
1 mg
Product is available in:
£52.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
75747-14-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C31H43N3O8
Molecular Weight:
585.7
Alternative Names:
17-
- MSDS: View or download
Product Description:
An inhibitor of Hsp90 (IC50s = 5 and 943 nM for BT474 tumor cell and fibroblast Hsp90, respectively); inhibits the growth of prostate cancer cell lines (IC50s = 25-45 nM); promotes the degradation of HER2 and induces growth arrest and apoptosis in breast cancer cells overexpressing HER2 (IC50s = 4-72 nM); reduces tumor size in a G-415 gallbladder cancer mouse xenograft model at 25 mg/kg
