Simvastatin (sodium salt)
Catalogue number:
CAY10010345-5 mg
Supplier:
Size:
5 mg
Product is available in:
£217.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
101314-97-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C25H39O6 • Na
Molecular Weight:
458.6
Alternative Names:
(βr,δr,1s,2s,6r,8s,8ar)-
Product Description:
An HMG-CoA reductase inhibitor (Ki = 0.12 nM); reduces plasma cholesterol levels in rats and dogs at 1.2 and 8 mg/kg, respectively; suppresses TNF-induced NF-κB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid leukemia cells; inhibits GPX4, increases MDA levels, and induces ferroptosis in MDA-MB-231 and MCF-7 breast cancer cells
