SUN-1334H free base
Catalogue number:
T87997-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
607737-00-8
Molecular Formula:
C23H26F2N2O3
Molecular Weight:
416.46
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- Protocol: View or download
Product Description:
SUN-1334H free base, an orally active histamine H1 receptor inhibitor, exhibits a K_i of 9.7 nM and an IC 50 of 20.3 nM. Additionally, it effectively prevents histamine-induced contractions in isolated guinea-pig ileum with an IC 50 of 0.198 µM. The compound also blocks histamine-induced bronchoconstriction and skin wheals in guinea pigs and beagle dogs, respectively, and mitigates ovalbumin-induced rhinitis in guinea pigs.