IRF1-IN-2
Catalogue number:
T203076-25 mg
Supplier:
Size:
25 mg
Product is available in:
CAS Number:
708245-32-3
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
IRF1-IN-2 (Compound I-19) is an inhibitor of IRF1. It reduces the recruitment of IRF1 to the CASP1 promoter and hinders cell death signaling pathways by inhibiting the cleavage of Caspase 1, GSDMD, IL-1, and PARP1, as well as by preventing the phosphorylation of TKB1. The compound also upregulates GPX4 and downregulates FACL4. Additionally, IRF1-IN-2 provides protective effects against skin inflammatory damage induced by ionizing radiation.