AM-2394
Catalogue number:
T3312-200 mg
Supplier:
Size:
200 mg
Product is available in:
CAS Number:
1442684-77-6
Purity:
≥98%
Molecular Formula:
C22H25N5O4
Molecular Weight:
423.46
Alternative Names:
AM2394
- Data sheet: View or download
- MSDS: View or download
Product Description:
AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximately 10-fold, exhibits moderate clearance and good oral bioavailability in multiple animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes.