DC-LC3in-D5
Catalogue number:
T61871-5 mg
Supplier:
Size:
5 mg
Product is available in:
CAS Number:
2868312-73-4
Purity:
≥98%
Molecular Formula:
C19H22Cl2N2O3
Molecular Weight:
397.3
- Data sheet: View or download
- MSDS: View or download
Product Description:
DC-LC3in-D5 is a potent and selective covalent inhibitor of LC3A/B that disrupts autophagy by covalently binding to Lys49 on LC3B (IC₅₀ = 200 nM), resulting in impaired LC3B lipidation, accumulation of the autophagy substrate p62, and a significant reduction in the formation of autophagosome vesicles.