Sp-8-Br-PET-cGMPS
Catalogue number:
T88611-50 mg
Supplier:
Size:
50 mg
Product is available in:
CAS Number:
172806-21-2
Molecular Formula:
C18H15BrN5O6PS
Molecular Weight:
540.28
- Data sheet: View or download
- MSDS: View or download
Product Description:
Sp-8-Br-PET-cGMPS is a membrane-permeable PKG activator and an inhibitor of the membrane-permeable retinal cGMP-gated ion channels (cGMP-gated ion channel). It also serves as an activator for cGMP-dependent protein kinase I α and β. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, Sp-8-Br-PET-cGMPS does not undergo metabolic side effects and exhibits stronger lipophilicity and permeability compared to Sp-8-pCPT-cGMPS. This compound is useful for investigating the role of the cGMP signaling pathway in the nervous system.