KAT6B (MORF) Chemiluminescent Assay Kit
KIAA0383, MORF, MOZ2, MYST4, lysine acetyltransferase 6B
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The KAT6B (MORF) Chemiluminescent Assay Kit is an ELISA-based assay designed to measure the histone acetyl transferase activity of KAT6B (lysine acetyltransferase 6B, also known as MORF) for screening and profiling applications. This kit comes in a convenient 96-well format with enough purified KAT6B (amino acids 710-1020), acetyl donor, pre-coated plate with histone substrate, all the reagents necessary for assay detection, and blocking buffer for 96 enzyme reactions. Figure 1. KAT6B (MORF) Chemiluminescent Assay Kit schematic. KAT6B protein is added to a plate pre-coated with a histone substrate in the presence of acetyl-CoA. After washing, an anti-acetyl-lysine antibody is added, followed by a secondary HRP-antibody. Lastly, HRP substrate is added and the chemiluminescence signal generated can be measured. The signal is proportional to the acetyltransferase activity of KAT6B.Need us to run inhibitor screens or profile your compounds against KAT1? Check out our Acethyltransferase Screening &Profiling Services.