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Co 101244 (hydrochloride)

Catalogue number:
CAY43192-10 mg
Supplier:
Size:
10 mg
Product is available in:
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£213.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

193356-17-1

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C21H27NO3 • HCl

Molecular Weight:

377.909

Alternative Names:

1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]-4-piperidinol, monohydrochloride, pd 174494

Product Description:

An antagonist of NR1A/2B subunit-containing NMDA receptors (IC50 = 0.043 µM); selective for NR1A/2B subunit-containing NMDA receptors over NR1A/2A and NR1A/2C subunit-containing NMDA receptors (IC50s = >100 µM for both); reduces the number of MES-induced seizures in mice (ED50 = 1.5 mg/kg)