MRT-92
Catalogue number:
T200033-100 mg
Supplier:
Size:
100 mg
Product is available in:
CAS Number:
1428315-82-5
Molecular Formula:
C33H34N4O5
Molecular Weight:
566.65
- Data sheet: View or download
- MSDS: View or download
Product Description:
MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.