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YSY01A

Catalogue number:
T200778-100 mg
Size:
100 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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CAS Number:

1194235-46-5

Molecular Formula:

C29H38BN5O5

Molecular Weight:

547.45

Product Description:

YSY01A is a proteasome inhibitor that suppresses cancer cell survival by inducing apoptosis (Apoptosis). It demonstrates IC50 values against various cell lines such as HEK293T, A549, MCF-7, MGC-803, and PC-3M with values of 51.01, 9.21, 5.21, 8.9, and 35.4 nM respectively. Additionally, YSY01A serves as a degrader of gp130 and JAK2, eliminating constitutive STAT3 signaling in human A549 lung cancer cells by downregulating gp130 and JAK2. YSY01A holds potential for research in cancer therapeutics.