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XMU-MP-9

Catalogue number:
T200189-100 mg
Size:
100 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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CAS Number:

2251130-41-1

Molecular Formula:

C19H13ClFN3OS

Molecular Weight:

385.84

Product Description:

XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.