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CDK8/19-IN-51

Catalogue number:
T22633-1 mg
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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CAS Number:

1860885-61-5

Purity:

≥98%

Molecular Formula:

C23H22N6O2

Molecular Weight:

414.46

Alternative Names:

CCT251545 analogue, Compound 51

Product Description:

CDK8/19-IN-51 is an orally active and highly effective dual inhibitor of CDK8 and CDK19, with anticancer activity. Its IC50 values for CDK8 and CDK19 are 5.1 nM and 5.6 nM, respectively. It is used in studies of colorectal and gastric cancers.